Biofilm Associated Diseases

Vastu Vihar Biotech has discovered a drug molecule that contains RNA and by using this drug, the biofilm layers of various bacteria responsible for causing biofilm-associated diseases can be degraded.

A biofilm is made of different types of microorganisms in which cells adhere to one another and regularly attaches to a surface. These adherent cells become embedded with a slimy extracellular matrix that is made up of lipid, RNA, DNA, polysaccharides which is difficult to remove because the bacteria make a thick protective layer and covers this layer like an umbrella so that no antibiotics works upon them due to which biofilm-associated disease cannot be treated easily.

Biofilm infections are often chronic in nature, since the biofilm-residing bacteria can be resilient to both the immune system, antibiotics, and other treatments. However, biofilms are usually associated with various pathogenic forms of human diseases and also plant infections, a common example is cystic fibrosis. Evidently, it also is the most frequently passed genetic disorder in some parts of the world.

According to researcher 12 patients per day dies due to biofilm-associated diseases.

There are various biofilm-associated diseases like Endocarditis, Septicemia, Meningitis, and Endophthalmitis which are extremely difficult to treat. Therefore, we are using the RNAi mechanism to degrade the bacterial biofilm, for which our main aim is to degrade the biofilm made by various bacteria with the help of RNA which is capable of treating various biofilm-associated diseases.

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